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WebSep 17, 2024 · Background: Dysfunctional humoral and cellular innate immunity are key components in the development and progression of age-related macular degeneration (AMD). Specifically, chronically activated microglia and their disturbed regulatory system contribute to retinal degeneration. Galectin-3, a β-galactose binding protein, is a potent … WebJul 14, 2024 · The late-stage pipeline also features several relative newcomers, including Fibrogen, Liminal Biosciences, and PharmAkea The late-stage pipeline also features several ... how fire starts
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WebJun 22, 2024 · GB0139 significantly reduced oxygen flow requirements and improved several biomarkers for lung and systemic inflammation, liver function, tissue damage and … WebFeb 4, 2024 · Detailed Description. This study is designed to evaluate the efficacy and safety of GB0139, a galectin-3 inhibitor, administered by dry powder inhalation over 52 weeks. … WebGalectin (Gal)-3 is a profibrotic β-galactoside-binding lectin that plays a key role in the pathogenesis of idiopathic pulmonary fibrosis (IPF) and IPF exacerbations. TD139 is a … how fire protection system works